Karen is an epidemiologist and modeler. She leads the Cancer Research Division at Cancer Council NSW Australia, and is the Director of The Daffodil Centre, a joint venture with The University of Sydney. The focus of her program of research is to provide policy-makers with an evidence-base for decision making in cancer control. Karen has led evaluations of new screening approaches for government agencies in several countries and currently leads a National Health and Medical Research Council Australia Centre of Research Excellence in Cervical Cancer Control (C4). Her team’s work underpins the transition of the National Cervical Screening Program in Australia to 5-yearly HPV-based screening. She currently has active collaborative modelling grants from the US NIH and WHO to model cervical cancer prevention in the USA and globally. She is also co-chair of the Steering Group for the Covid-19 and Cancer Global Modelling Consortium (CCGMC.org) which is supported by UICC, the International Agency for Research on Cancer, The International Cancer Screening Network, and the Canadian Partnership against Cancer. The CCGMC aims to quantify the global impact of the pandemic and assist in recovery planning for cancer outcomes.